Grapefruit juice can block the action of CYP3A4, which means more of the medication enters the bloodstream and stays in the body for longer.
As people have differing amounts of the enzyme in their small intestine, grapefruit juice can affect people differently, even if they’re taking the same medication.
The FDA confirmed that mixing grapefruit and statins could lead to an increased risk for liver and muscle damage.
These two side effects may even lead to kidney failure, which is a serious complication.
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